Facts - Prevention - Testing - Terminology - FAQs - Tough Questions about CMV

Facts about Cytomegalovirus (CMV)

Cytomegalovirus, or CMV, is found universally throughout all geographic locations and socioeconomic groups, and has infected between 50% and 85% of adults in the United States by 40 years of age. CMV is also the virus most frequently transmitted to a developing child before birth.


Each year in the United States approximately 30,000 children are born with congenital CMV causing an estimated 400 deaths and leaving approximately 8,000 children with permanent disabilities such as hearing or vision loss, or mental retardation. It is estimated that 1 in every 150 children are born infected with congenital CMV. More children are adversely affected by congenital CMV than by several better-known childhood diseases or syndromes such as Down Syndrome, Fetal Alcohol Syndrome and Spina Bifida.

How CMV effects Pregnancy

The incidence of primary (or first) CMV infection in pregnant women in the United States varies from 1% to 3%. When infected with CMV, most women have no symptoms and very few have symptoms resembling mononucleosis.

Temporary problems (at birth) include the following:

Hearing Loss, Vision Loss, Mental Disability, Lung Problems, Bleeding Problems, Spleen Problems, Liver Problems, Growth Problems


Permanent problems include the following:

Hearing loss, Vision loss, Mental disability, Feeding issues/Failure to Thrive (FTT), Sleeping issues, Sensory issues, ADHD/Autism, Small head/small brain (Microcephaly), Intercranial Calcifications, Cerebral palsy, Seizures, Death


For infants who are infected by their mothers during pregnancy, two potential problems exist:

  • Generalized infection may occur in the infant and symptoms may range from moderate enlargement of the liver and spleen to fatal illness. With supportive treatment, most infants with CMV disease usually survive. However, 80% to 90% will have complications within the first few years of life that may include hearing loss, vision impairment, and varying degrees of mental retardation.
  • Another 5% to 10% of infants who are infected but without symptoms at birth will subsequently have varying degrees of hearing and mental or coordination problems.
Transmission of CMV

CMV can be transmitted to the unborn child of a mother with a primary CMV infection.

When a baby catches CMV prior to birth, it is known as a congenital CMV infection. Approximately 90% of all infants who are infected with CMV prior to delivery are born without symptoms of the virus but may go on to develop disabilities due to CMV infection. The remaining 10% who are born with visible symptoms of the virus will have varying degrees of abnormalities. It is estimated that up to 20 percent of babies born with symptomatic CMV infection will die.

Transmission of the virus is often preventable because it is most often transmitted through infected bodily fluids (saliva, urine, tears, blood, mucus, etc) that come in contact with hands and then are absorbed through the nose or mouth of a susceptible person.

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High-risk Groups

CMV infection is very common in daycare settings, especially among children 1 to 3 years of age who are at high risk for CMV infection. Women who work with infants and young children should be educated about the risks of CMV and the precautions they can take to prevent infection. Child care providers (meaning daycare workers, teachers, therapists, as well as mothers) should be diligent in handwashing, as they are at increased risk for exposure to the virus. They should also not share drinks or food with small children.

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